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Papers citing cellQART®

Peer-reviewed scientific publications of our users around the globe



Migration/Invasion assays

Published: June 01, 2023

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Monittola, F. et al. Gastric cancer cell types display distinct proteasome/immunoproteasome patterns associated with migration and resistance to proteasome inhibitors. J. Cancer Res. Clin. Oncol. (2023) doi:10.1007/s00432-023-04948-z.

Keywords: Proteasome; Immunoproteasome; Gastric cancer; Cell migration; Proteasome inhibitiors; 20S regulatory particles

Published: January 20, 2023

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Moran, J. et al. Investigating the Effects of Olaparib on the Susceptibility of Glioblastoma Multiforme Tumour Cells to Natural Killer Cell-Mediated Responses. Pharmaceutics 15, 360 (2023).  

Keywords: NK cells; Glioblastoma multiforme; immunotherapy; Olaparib; PARP Inhibitor

Published: December 27, 2022

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Taffoni, C. et al. DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma. The EMBO Journal 42, e111961 (2023).

Keywords: cGAS; DNA-PK; inflammation; tumor immunogenicity

Published: March 21, 2022

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Dacheux, M. A. et al. Prometastatic Effect of ATX Derived from Alveolar Type II Pneumocytes and B16-F10 Melanoma Cells. Cancers 14, 1586 (2022).

Keywords: autotaxin; lysophosphatidic acid; metastasis; B16-F10; melanoma; alveolar type II cells; tumor microenvironment; tumor immunity


Tissue engineering

Published: January 26, 2023

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Nakamura, T. et al. Aß42 treatment of the brain side reduced the level of flotillin from endothelial cells on the blood side via FGF-2 signaling in a blood-brain barrier model. Mol Brain 16, 15 (2023).

Keywords: Alzheimer´s disease; Amyloid ß-protein; Blood flotillin; Microvascular endothelial cells

Published: April 26, 2023

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Phan, T. H. et al. Advanced pathophysiology mimicking lung models for accelerated drug discovery. Biomaterials Research 27, 35 (2023). 

Keywords: Lung-mimicking models; Multimodal characterisation; Physiological relevance; Microcirculation; Extracellular matrix; Patient-derived cell lines; Personalised medicine

Published: September 15, 2022

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Cegarra, C. et al. An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family. PLOS ONE 17, e0274667 (2022).

Keywords: antibody binding capacity; blood brain barrier; brain microvascular endothelial cells; human cerebral microvascular endothelial cell; apparent permeability; receptor-mediated transcytosis; teer; trans-endothelial electrical resistance

Note: PharmaCo-Cell® BBB Kits incorporate cellQART® Cell Culture Inserts

Published: July 14, 2022

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Hansen, R. H. et al. Increased Intrathecal Activity of Follicular Helper T Cells in Patients With Relapsing-Remitting Multiple Sclerosis. Neurol. - Neuroimmunol. Neuroinflammation 9, (2022).

Keywords: blood-brain barrier; human brain microvascular endothelial cells; immunoglobulin G; interferon; interleukin; melanoma cell adhesion molecule 1; multiple sclerosis; peripheral blood mononuclear cells; programmed cell death protein 1; TEER; transendothelial electrical resistance

Published: June 07, 2022

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von Essen, M. R. et al. Ofatumumab Modulates Inflammatory T Cell Responses and Migratory Potential in Patients With Multiple Sclerosis. Neurol. Neuroimmunol. Neuroinflammation 9, e200004, (2022).

Keywords: blood-brain barrier; dendritic cell; human brain microvascular endothelial cell; myelin basic protein; myelin oligodendrocyte glycoprotein; multiple sclerosis; peripheral blood mononuclear cell; transendothelial electrical resistance



Published: April 03, 2023

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Li, P. et al. Mpox virus infects and injures human kidney organoids, but responding to antiviral treatment. Cell Discov. 9, 1–4 (2023).

Keywords: Kidney organoids; monkey pox virus; infection; antiviral



Published: June 26, 2023

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Fetahu, I. S. et al. Single-cell transcriptomics and epigenomics unravel the role of monocytes in neuroblastoma bone marrow metastasis. Nat. Commun. 14, 3620 (2023).

Keywords: Single-cell transcriptomics; epigenomics; monocytes; neuroblastoma; metastasis

Published: May 31, 2023

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Subayyil, A. A. et al. Preconditioned Chorionic Villus Mesenchymal Stem/Stromal Cells (CVMSCs) Minimize the Invasive Phenotypes of Breast Cancer Cell Line MDA231 In Vitro. Int. J. Mol. Sci. 24, 9569 (2023).

Keywords: HMECs; MDA231; adhesion; chorionic villus MSCs; conditioned media; epithelial to mesenchymal transition (EMT); flow cytometry; flow cytometry; invasion; migration; proliferation

Published: March 31, 2023

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Pop, O.-T. et al. AXL Expression on Homeostatic Resident Liver Macrophages Is Reduced in Cirrhosis Following GAS6 Production by Hepatic Stellate Cells. Cell. Mol. Gastroenterol. Hepatol. 0, (2023).

Keywords: TAM Receptors; Innate Immunity; Cirrhosis; Resident Liver Macrophages

Published: January 01, 2023

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Hameedat, F., Pinto, S., Marques, J., Dias, S. & Sarmento, B. Functionalized zein nanoparticles targeting neonatal Fc receptor to enhance lung absorption of peptides. Drug Deliv. and Transl. Res. 13, 1699–1715 (2023).

Keywords: Peptides delivery; Neonatal Fc receptor; Lung absorption; Targeted nanoparticles; Zein nanoparticles; PEGylation; Permeability assay

Published: December 10, 2021

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Basmaeil, Y. et al. Decidua Parietalis Mesenchymal Stem/Stromal Cells and Their Secretome Diminish the Oncogenic Properties of MDA231 Cells In Vitro. Cells 10 , 3493 (2021).

Keywords: placenta; decidua parietalis MSCs; MDA231; conditioned medium; adhesion; proliferation; migration; invasion; angiogenesis

Published: November 12, 2021

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Nintou, E. et al. Effects of In Vitro Muscle Contraction on Thermogenic Protein Levels in Co-Cultured Adipocytes. Life Basel Switz. 11 , 1227 (2021).

Keywords: EPS; UCP1; adipocytes; muscle contraction; myotubes; thermogenesis


Epithelial cell cultures

Published: November 2, 2022

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Gelli, H. P., Vazquez-Uribe, R. & Sommer, M. O. A. Screening for effective cell-penetrating peptides with minimal impact on epithelial cells and gut commensals in vitro. Front. Pharmacol. 13, (2022).

Keywords: cell-penetrating peptides, cytotoxicity, permeation enhancer, cell viability, gut microbiota, intestinal absorption, caco-2 cells, in vitro

Published: January 31, 2022

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Ngo, T. T. T. et al. Functional differentiation and scalable production of renal proximal tubular epithelial cells from human pluripotent stem cells in a dynamic culture system. Cell Prolif. e13190 (2022).

Keywords: Pluripotent stem cells; alginate; bioreactor; functional tubular epithelial cells; kidney differentiation


Enzymatic degradation tests

Published: June 17, 2022

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Lutz, T. M., Kimna, C. & Lieleg, O. A pH-stable, mucin based nanoparticle system for the co-delivery of hydrophobic and hydrophilic drugs. Int. J. Biol. Macromol. 215, 102–112 (2022). 

Keywords: glycoprotein; hesperidin; β-Carotene; swelling; enzymatic degradation tests



Published: July 18, 2023

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Cuanalo-Contreras, K., Hogrebe, A. M. R., Teichmann, K. & Benkmann, D. Track-Etched Membranes for Drug Pharmaceutical Research. Chem. Ing. Tech. 95, 1372-1380(2023).

Keywords: drug development; organs-on-a-chip; tissue engineering; toxicology; track-etched membranes

Published: January 19, 2022

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Polesca, C., Passos, H., M. Neves, B., P. Countinho, J. A. & G. Freire, M. Valorization of chicken feathers using aqueous solutions of iconic liquids. Green Chemistry 25, 1424-1434(2023).

Keywords: Keratin film; monocytes; macrophages; keratinocytes; fibroblasts

Published: February 20, 2022

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Cuanalo-Contreras, K. & Benkmann, D. et al. Towards More Human and Humane Testing: The Role of the Device Supplier Industry. Altern. Lab. Anim. ATLA 2611929211073132 (2022).

Keywords: animal-free; cell culture; cosmetic testing; drug discovery; in vitro; new approach methodologies; supplier industry; toxicology

Published: January 31, 2022

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Wu, X. et al. Localised light delivery on melanoma cells using optical microneedles. Biomed. Opt. Express 13 , 1045–1060 (2022).

Keywords: light-based therapy; skin cancer; in vitro; B16F10 melanoma cells

Published: July 6, 2021

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Singh, B. et al. Towards More Predictive, Physiological and Animal-free In Vitro Models: Advances in Cell and Tissue Culture 2020 Conference Proceedings. Altern. Lab. Anim. ATLA 49 , 93–110 (2021).

Keywords: 3-D; 3Rs; Three Rs; animal replacement; animal-free; in vitro; microphysiological system; new approach methodologies; organ-on-a-chip; organoid; tissue microenvironment