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November 21, 2023 Press

New Paper: DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma

New insights in cell culture – dive into research with us | paper series part 4

In this paper, Taffoni et al. used glioblastoma cells with undetectable levels of cyclic GMP-AMP synthase to address whether alternative DNA recognition pathways can promote pro-inflammatory signalling. Our cellQART 3 micron clear inserts were used to perform migration assays with the THP-1 myeloid cell line.


Source: Taffoni, C. et al. DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma. The EMBO Jorunal 42, e111961 (2023).